Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPF All Species: 9.09
Human Site: S3007 Identified Species: 16.67
UniProt: P49454 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49454 NP_057427.3 3210 367764 S3007 G P V V P G P S P I P S V T E
Chimpanzee Pan troglodytes XP_001171549 3114 357698 S2911 D P V V P G P S P I P S V T E
Rhesus Macaque Macaca mulatta XP_001105956 3113 357422 S2910 D P V V P G P S P I L S A A E
Dog Lupus familis XP_852813 1449 166096 S1252 K V Q M S E E S K T A V G M L
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510329 2965 340022 A2757 P S Q C A G H A A K S P V H L
Chicken Gallus gallus O42184 1433 161009 K1236 T S A L I T Q K D E E L E K L
Frog Xenopus laevis P85120 2058 236320 A1861 R G N S L S R A F S L A S A D
Zebra Danio Brachydanio rerio XP_002665261 2708 311087 S2511 K T P K S R R S L R S E T S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJE5 1690 189046 A1493 D A A S V K S A L L E Q L Q N
Honey Bee Apis mellifera XP_001120388 2064 240016 N1867 C N E Y V E A N K I L R K N F
Nematode Worm Caenorhab. elegans P02566 1966 225108 K1769 A A E E R S K K A I A D A T R
Sea Urchin Strong. purpuratus XP_796801 3636 416057 D3292 T V P E I N K D E V A P V Q E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25386 1790 206434 N1593 T V K Q E L N N A Q E K I R I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 91.4 32.8 N.A. N.A. N.A. N.A. 50.5 20.4 21.5 31.3 N.A. 21.3 22.9 20.1 22
Protein Similarity: 100 96.4 93.8 39.1 N.A. N.A. N.A. N.A. 67.5 32.4 38.6 51.2 N.A. 35.2 41.3 36.4 43.7
P-Site Identity: 100 93.3 73.3 6.6 N.A. N.A. N.A. N.A. 13.3 0 0 6.6 N.A. 0 6.6 13.3 13.3
P-Site Similarity: 100 93.3 73.3 13.3 N.A. N.A. N.A. N.A. 20 6.6 20 20 N.A. 20 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 16 0 8 0 8 24 24 0 24 8 16 16 0 % A
% Cys: 8 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 24 0 0 0 0 0 0 8 8 0 0 8 0 0 16 % D
% Glu: 0 0 16 16 8 16 8 0 8 8 24 8 8 0 31 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 8 8 0 0 0 31 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 16 0 0 0 0 39 0 0 8 0 8 % I
% Lys: 16 0 8 8 0 8 16 16 16 8 0 8 8 8 0 % K
% Leu: 0 0 0 8 8 8 0 0 16 8 24 8 8 0 24 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 8 8 0 0 8 8 16 0 0 0 0 0 8 8 % N
% Pro: 8 24 16 0 24 0 24 0 24 0 16 16 0 0 0 % P
% Gln: 0 0 16 8 0 0 8 0 0 8 0 8 0 16 0 % Q
% Arg: 8 0 0 0 8 8 16 0 0 8 0 8 0 8 8 % R
% Ser: 0 16 0 16 16 16 8 39 0 8 16 24 8 8 0 % S
% Thr: 24 8 0 0 0 8 0 0 0 8 0 0 8 24 0 % T
% Val: 0 24 24 24 16 0 0 0 0 8 0 8 31 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _